THESIS STUDENTS

Deepwanita Chakrabarty

Master of Science in Biotechnology

Thesis Title: Spatiotemporal Patterns of Antimicrobial Resistance in Bacteria Over the Past Two Decades

Deepwanita's research focuses on mapping global antimicrobial resistance trends over the last 20 years. Her work analyzes key geographic and temporal patterns and sheds light on the evolution and spread of resistance genes.

Presented at: 5th ICBHA 2023 Conference.

Current Status: Completing her Ph.D at the University of Missouri- 

Rian Rafsan

Master of Science in Biotechnology

Thesis Title: Demystifying Lanthanomes: A Pangenomic Approach

Rian’s research explores lanthanome systems through a pangenomic lens, aiming to uncover the role of lanthanides in microbial metabolism and their potential biotechnological applications.

Presented at: 37th BSM Annual Conference 2023.

Current Status: Research Assistant, Microbiology program, Department of Mathematics and Natural Sciences, BRAC University

Tanzeem Fatima

Master of Science in Biotechnology

Thesis Title: Unveiling the Mode of Action of Bacteriophage JSF7 in Infecting Its Host, Vibrio cholerae.

Tanzeem's research focuses on uncovering the mode of action of the Vibrio cholerae bacteriophage JSF7. By studying hypothetical proteins using bioinformatic approaches, she identified the operon responsible for infection. This unique bacteriophage has the potential to degrade biofilm, a key factor in antibiotic resistance.

Current Status: Ongoing Master’s thesis research.

Protik Roy

Master of Science in Biotechnology

Thesis Title:  The Relationship Between Prophages and Self-Targeting Spacers in Diverse Bacteria

Protik’s bioinformatic research delves into the relationship between self-targeting spacers (STS) and prophages across diverse bacterial species. His work aims to determine whether the occurrence of STS correlates with prophage-derived pathogenicity.

Current Status: Ongoing Master’s thesis research.

Ratul Reza

Bachelor of Science in Biotechnology

Thesis Title:  Distribution of Complete CRISPR-Cas Systems in Vibrio cholerae and Its Effect on Plasmid-Derived Contigs in Complete Genome Assemblies

Ratul's research focuses on the interaction between CRISPR-Cas systems and plasmids in Vibrio cholerae. By analyzing 5,873 genomic assemblies using machine learning tools like PlasForest for plasmid prediction and CRISPRCasTyper for CRISPR-Cas system identification, his study revealed a significant decrease in plasmid-derived contigs (PDC) in genomes with CRISPR-Cas systems.

Current Status: Graduated after successfully defending his thesis.

Nabiha Nuha

Bachelor of Science in Biotechnology

Thesis Title:  In Silico Analysis Reveals hsa-miR-19a-3p and hsa-miR-19b-3p as Potential Inhibitors of EGF mRNA in Breast Cancer

Nabiha's research focuses on the role of microRNAs in inhibiting breast cancer cell growth by targeting the Epidermal Growth Factor (EGF) gene. Using in silico analysis, she identified two miRNAs, hsa-miR-19a-3p and hsa-miR-19b-3p, that could potentially block EGF mRNA, thereby inhibiting tumor-promoting pathways.

Current Status: Graduated after successfully defending her thesis.

Radiya Tum Mardia & Umaiya Binte Mahbub

Bachelor of Science in Biotechnology

Thesis Title: In-Silico Approach to Design a Novel Multi-Epitope Vaccine Against Zika Virus

Their research aimed to develop a multi-epitope vaccine against the Zika virus using computational immunoinformatics and bioinformatics. Their study identified potential vaccine candidates targeting key structural proteins, which were shown to be non-allergenic, non-toxic, and highly antigenic through thorough in silico validation.

Current Status: Graduated after successfully defending her thesis.

Inshera Ahmed, Sultan Shanneedh Quader & Jakia Tahsin Juspy

Bachelor of Science in Biotechnology

Thesis Title: A Comparative Proteomic Study of Salt Tolerance in Arabidopsis thaliana to Identify Strategies for Improving Salt Tolerance in Solanum lycopersicum

This collaborative research investigates salt tolerance mechanisms by comparing proteins in Arabidopsis thaliana with those in Solanum lycopersicum (tomato). The study aimed to identify tomato proteins similar to those in Arabidopsis known for salt tolerance and explore potential gene editing strategies to enhance salt tolerance in tomatoes. The comparison of 5 Arabidopsis proteins with the tomato proteome revealed several proteins with significant similarities but also highlighted numerous mutations.

Current Status: Graduated after successfully defending their thesis.

Adil Ahnaf, Aryan Kabir & Anata Choudhury

Bachelor of Science in Biotechnology

Thesis Title: Investigating Plasmid Mispackaging in Bacteriophages and Its Role in Horizontal Gene Transfer

Their research explores the mispackaging of plasmids inside bacteriophages and its potential contribution to horizontal gene transfer. Their work focuses on understanding the frequency of plasmid mispackaging, the environmental factors influencing this process, and its implications for genetic material transfer.

Current Status: Ongoing undergraduate thesis research.

Md. Sakibul Islam Santa

Bachelor of Science in Biotechnology

Thesis Title: Profiling Pathogenic Factors and Microbial Diversity in Human Gut Metagenome Sequences

Sakibul is investigating the metagenome sequences of the human gut to profile various pathogenic factors, microbial types, sources of antibiotic resistance, and the abundance of bacteriophages.

Current Status: Ongoing undergraduate thesis research.

Syeda Tamanna Tarannum

Bachelor of Science in Microbiology

Thesis Title: Genomic Profiling of Pathogenic Factors and Antibiotic Resistance in Acinetobacter baumannii

Tamanna’s research focuses on the genome sequences of Acinetobacter baumannii, profiling pathogenic factors, antibiotic resistance genes, plasmids, and analyzing the temporal and spatial distribution of antimicrobial resistance (AMR).

Current Status: Ongoing undergraduate thesis research

Chandrima Datta

Bachelor of Science in Biotechnology

Thesis Title: Profiling Pathogenicity Factors Derived from Prophages in Diverse Bacterial Genomes

Chandrima's research focuses on how prophages contribute to bacterial pathogenicity by identifying factors that enhance virulence and understanding their impact on bacterial evolution.

Current Status: Ongoing undergraduate thesis research.